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The International Center for Research on Women (ICRW) and Taasisi ya Maendeleo Shirikishi Arusha (TAMASHA), in collaboration with Pact Tanzania, developed a participatory research and action project (Vitu Newala) that aimed to both understand and respond to girls’ HIV-related vulnerabilities. The project was conducted in Newala, one of the least developed and poorly resourced districts of Tanzania.